Microfluidic surface treatment plan

Channel hydrophilic modification to modify: polydimethylsiloxane ( PDMS) Since it has good light penetration, non-toxic, low cost, easy and other sealing materials, easy to make, can be mass production, as well as good biocompatibility, contribution to the construction of multi-function microfluidic chip device has been widely used and development. But because of PDMS microchip channel surface electric charge quantity is less, electric seepage ( EOF) Instability, the surface has strong hydrophobic properties, easy adsorption measured components such as faults, this greatly limits the analysis can be conducted on PDMS microchip separation material types, and reduces the analyte separation efficiency, and greatly influences the application range of PDMS microfluidic chips. On PDMS microfluidic chip proper channel surface modification and modification, to effectively control the size of the EOF, can improve the hydrophilicity on the surface of the PDMS microfluidic chip, reduce the biological molecules in PDMS microchannel nonspecific adsorption on the surface of the chip, so as to improve the separation efficiency of analytes.



in micro concave lines of PDMS substrate polyacrylic covalent modification, the formation of hydrophobic pattern. Establish a PDMS photocatalytic modification technology, and puts forward two kinds of surface treatment solutions respectively after bonding with bonding by modifying PDMS substrate/chip so as to change the electric seepage of microchannel.



the various material chip surface can be chemical deposition, water can do hydrophobic modification can also become relatives by marriage.