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Microfluidic chip 2019 frontier seminar
by：Transon
2021-01-08
2019 (
The third)
Microfluidic chip frontier seminar will be October 25 - in 2019
26, held in Shanghai.
The well-known experts in the field of this conference will invite and disciplines spokesperson, industry pioneer discuss microfluidic chip brings to the basic research and clinical diagnosis and treatment of huge changes, also discuss the microfluidic in vitro diagnosis, food safety, environmental monitoring, etc, the industry opportunities.
lecture topic: organ chip and its microenvironment
abstract: speech organs chip is international economic BBS elected in 2016, one of the top ten emerging technologies, and self-driving cars, 2 d material graphene. Chip is composed of two most organs, one is the ontology, the corresponding cells according to the proportion of solid organ and sequence set, the second is the micro environment, including other cells surrounding the chip organ, cell secretion and physical force. Organ chip simulation degree of strength and micro environment construction and the related. Author's laboratory has developed different types of organ chips, such as liver, kidney, pancreas, tumor, and the integration of multiple organ, and the activity and toxicity screening of drugs. At the same time, the laboratory is focused on the further research of chip organ microenvironment.
we use single cell antibody barcode based on microfluidic chip, respectively up to thousands of living cell secreted by a variety of protein molecules at the same time test, dynamic test and a variety of vesicle detection at the same time. We also cooperate with the south university of science and technology, the microfluidic technology and semiconductor active matrix technology combined with digital droplets carrying out a research into the microfluidic digital droplet central processing unit (CPU), be used for large-scale, eight and discharge the pick up of a single cell, two completely different chip depth docking study the possibility of chip organ microenvironment.
we are in the glomerular chip physical model on the basis of building the mechanical environment of a simulated glomerular hypertension kidney pathology model, and the pathologic model representation, high blood pressure, kidney disease early renal hemodynamics was studied the influence of the change of glomerular filtration barrier function and its molecular mechanism, and spontaneously hypertensive rats ( 月) Confirmed the glomerular pathology chip model studies the feasibility of high blood pressure, kidney disease.
lecture topic: Raman flow cytometry sorting based on microfluidic technology
abstract: speech single cell is the basic functional unit of the life activities. Cell level of the existing based on groups of gene sequencing and measurement is an average measurement function, can't accurate reaction cell heterogeneity. The operation of the single cell level and analysis technology at an unprecedented depth and precision to parse the mysteries of life. ” Single-celled Raman spectrum & quot; Is certain cells & quot; Chemical fingerprints & quot; , contains the specific cells of abundant biological information in specific physiological conditions, through the cell chemical composition and its changes, to static and dynamic characterization and monitoring of the cell's genetic background, physiological state and micro environment. Especially important, because each Raman spectrum peaks in the Raman spectra or a collection of several Raman spectrum peak potential represents a phenotype, therefore, Raman spectra can be in a single cell precision & quot; Panoramic & quot; Characterization of cell groups or communities of & quot; State & quot; With & quot; Function & quot; 。 Compared with the existing fluorescent cells sorting technology both FACS, Raman spectra activated cell sorting RACS has the characteristics of the condition of tag.
this report will focus on in our laboratory in recent years, research and development of series of Raman single-cell analysis/sorting/sequencing technologies and in rapid detection of antibiotic resistance and cellular functions, high-throughput screening applications in progress.
lecture topic: microfluidic POCT nucleic acid analysis
abstract: speech from traditional nucleic acid analysis method, is introduced based on microfluidic nucleic acid analysis technology, especially for POCT field study of rapid detection of nucleic acid diagnosis methods. The main contents include: ( 1) Sample pretreatment methods, including sampling, sample filter methods of red blood cells; ( 2) Nucleic acid extract methods, including solid phase extraction based media such as film, magnetic beads of microfluidic nucleic acid extraction method; ( 3) Nucleic acid amplification method quickly, including based on LAMP isothermal reaction, and based on the convection PCR detection method for nucleic acid amplification; ( 4) Integrated analysis of nucleic acids microfluidic systems, including with PCR diagnostic reagent storage integration chip, and centrifugal convection PCR analysis system integration, etc. Finally, the microfluidic POCT nucleic acid analysis, summarized the developing direction and trend of summary.
lecture topic: organ chip and its microenvironment
abstract: speech organs chip is international economic BBS elected in 2016, one of the top ten emerging technologies, and self-driving cars, 2 d material graphene. Chip is composed of two most organs, one is the ontology, the corresponding cells according to the proportion of solid organ and sequence set, the second is the micro environment, including other cells surrounding the chip organ, cell secretion and physical force. Organ chip simulation degree of strength and micro environment construction and the related. Author's laboratory has developed different types of organ chips, such as liver, kidney, pancreas, tumor, and the integration of multiple organ, and the activity and toxicity screening of drugs. At the same time, the laboratory is focused on the further research of chip organ microenvironment.
we use single cell antibody barcode based on microfluidic chip, respectively up to thousands of living cell secreted by a variety of protein molecules at the same time test, dynamic test and a variety of vesicle detection at the same time. We also cooperate with the south university of science and technology, the microfluidic technology and semiconductor active matrix technology combined with digital droplets carrying out a research into the microfluidic digital droplet central processing unit (CPU), be used for large-scale, eight and discharge the pick up of a single cell, two completely different chip depth docking study the possibility of chip organ microenvironment.
we are in the glomerular chip physical model on the basis of building the mechanical environment of a simulated glomerular hypertension kidney pathology model, and the pathologic model representation, high blood pressure, kidney disease early renal hemodynamics was studied the influence of the change of glomerular filtration barrier function and its molecular mechanism, and spontaneously hypertensive rats ( 月) Confirmed the glomerular pathology chip model studies the feasibility of high blood pressure, kidney disease.
lecture topic: Raman flow cytometry sorting based on microfluidic technology
abstract: speech single cell is the basic functional unit of the life activities. Cell level of the existing based on groups of gene sequencing and measurement is an average measurement function, can't accurate reaction cell heterogeneity. The operation of the single cell level and analysis technology at an unprecedented depth and precision to parse the mysteries of life. ” Single-celled Raman spectrum & quot; Is certain cells & quot; Chemical fingerprints & quot; , contains the specific cells of abundant biological information in specific physiological conditions, through the cell chemical composition and its changes, to static and dynamic characterization and monitoring of the cell's genetic background, physiological state and micro environment. Especially important, because each Raman spectrum peaks in the Raman spectra or a collection of several Raman spectrum peak potential represents a phenotype, therefore, Raman spectra can be in a single cell precision & quot; Panoramic & quot; Characterization of cell groups or communities of & quot; State & quot; With & quot; Function & quot; 。 Compared with the existing fluorescent cells sorting technology both FACS, Raman spectra activated cell sorting RACS has the characteristics of the condition of tag.
this report will focus on in our laboratory in recent years, research and development of series of Raman single-cell analysis/sorting/sequencing technologies and in rapid detection of antibiotic resistance and cellular functions, high-throughput screening applications in progress.
lecture topic: microfluidic POCT nucleic acid analysis
abstract: speech from traditional nucleic acid analysis method, is introduced based on microfluidic nucleic acid analysis technology, especially for POCT field study of rapid detection of nucleic acid diagnosis methods. The main contents include: ( 1) Sample pretreatment methods, including sampling, sample filter methods of red blood cells; ( 2) Nucleic acid extract methods, including solid phase extraction based media such as film, magnetic beads of microfluidic nucleic acid extraction method; ( 3) Nucleic acid amplification method quickly, including based on LAMP isothermal reaction, and based on the convection PCR detection method for nucleic acid amplification; ( 4) Integrated analysis of nucleic acids microfluidic systems, including with PCR diagnostic reagent storage integration chip, and centrifugal convection PCR analysis system integration, etc. Finally, the microfluidic POCT nucleic acid analysis, summarized the developing direction and trend of summary.
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