Jinan Transon CNC Equipment Co., Ltd.
S I N C E 2 0 1 0
Medical school dedicated microfluidic device makes experimental research on more efficient!
by：Transon
2021-01-08
Through the nano molecular targeted drug delivery system of drug combination of drugs and chemicals, in the case of low dose intravenous, can inhibit human skin factor receptor positive breast tumor 2 to 90%.
The findings, published online in the well-known academic journal PNAS.
Compared with the traditional process, microfluidic technology can greatly improve the production of particle uniformity, greatly increase the drug loading efficiency, and can achieve high throughput of industrial production.
researchers microfluidics breasts system is put forward, which is very efficient implementation of packaging a variety of hydrophobic and hydrophilic substances. Mesoporous silica nanoparticles has very good biocompatibility, biodegradable, high drug-loading rate and surface functionalized modifications, etc. The gold nanoparticles are widely used in biological imaging and thermal treatment. In the project, the team first combine gold nanorods by chemical reaction in mesoporous silica surface, and then through the mesoporous silica with a large number of hydrophilic and hydrophobic and protein and nucleic acid drugs, and through the method of microfluidics breasts step wrap mesoporous silica in the polymer as the main body, at the same time the giant of compound phosphatide vesicles. Then, based on the regulation of film extrusion build out of the drug at the same time, the load of drug-loading nanoparticles.
the nanoparticles drug system in positive HER2 breast cancer mouse model. The nanometer system has very good biocompatibility, and can be long reside in tumor. Through the continuous injection of the nanometer system, mice tumor inhibition rate of more than 90%, and the system greatly reduces the drug resistance of cancer cells and drugs cause side effects.
because the nanometer system has universality, this method could be widely applied to other types of cancer and other types on the treatment of diseases. And because the preparation method is simple and effective, the research team believes this method has the potential to clinical transformation. Hope the team of new medicine system, nanoparticles could eventually help more to improve outcomes for patients with cancer.
microfluidic chip to make the best equipment: HZZ - endeavour V3000( 我。 LASER3000/4000) Details please contact us.
researchers microfluidics breasts system is put forward, which is very efficient implementation of packaging a variety of hydrophobic and hydrophilic substances. Mesoporous silica nanoparticles has very good biocompatibility, biodegradable, high drug-loading rate and surface functionalized modifications, etc. The gold nanoparticles are widely used in biological imaging and thermal treatment. In the project, the team first combine gold nanorods by chemical reaction in mesoporous silica surface, and then through the mesoporous silica with a large number of hydrophilic and hydrophobic and protein and nucleic acid drugs, and through the method of microfluidics breasts step wrap mesoporous silica in the polymer as the main body, at the same time the giant of compound phosphatide vesicles. Then, based on the regulation of film extrusion build out of the drug at the same time, the load of drug-loading nanoparticles.
the nanoparticles drug system in positive HER2 breast cancer mouse model. The nanometer system has very good biocompatibility, and can be long reside in tumor. Through the continuous injection of the nanometer system, mice tumor inhibition rate of more than 90%, and the system greatly reduces the drug resistance of cancer cells and drugs cause side effects.
because the nanometer system has universality, this method could be widely applied to other types of cancer and other types on the treatment of diseases. And because the preparation method is simple and effective, the research team believes this method has the potential to clinical transformation. Hope the team of new medicine system, nanoparticles could eventually help more to improve outcomes for patients with cancer.
microfluidic chip to make the best equipment: HZZ - endeavour V3000( 我。 LASER3000/4000) Details please contact us.
Custom message
